depression
Psychedelic treatments have sparked considerable interest in recent years, with several studies suggesting their potential to treat depression. However, how these substances compare to traditional antidepressants has been a subject of ongoing debate. A recent systematic review and meta-analysis published in The BMJ sheds light on this topic, focusing on the effectiveness of psychedelics, particularly psilocybin, compared to the commonly prescribed antidepressant, escitalopram. The study’s findings reveal that among the psychedelics analyzed, only high-dose psilocybin showed greater effectivene...
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More than 85% of women – and more than 300 million people worldwide at any given time – use hormonal contraceptives for at least five years of their life. Although primarily taken for birth control, many people also use hormonal contraceptives to manage a variety of symptoms related to menstruation, from cramps and acne to mood swings. For up to 10% of women, however, hormone contraceptives can increase their risk of depression. Hormones, including estrogen and progesterone, are crucial for brain health. So, how does modifying hormone levels with hormone contraceptives affect mental health? I ...
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A new meta-analysis has reported that individuals with a high triglyceride-glucose index have a 41% greater likelihood of suffering from depression compared to those with lower values of this index. These results remained consistent across individuals both above and below 50 years of age, as well as across different genders. The research was published in Frontiers in Psychiatry. Depression is a common mental health disorder characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. The severity of depression can vary, and it can be influenc...
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Depression in young people is a growing concern. A new study published in the Journal of Affective Disorders explores an innovative approach to enhance current treatments: computerized memory specificity training. The findings suggest that this type of cognitive training could help young people with depression recall specific memories better and reduce depressive symptoms over time. Major depressive disorder is a prevalent and impactful mental illness, with youth experiencing higher rates of recurrence and poorer outcomes compared to other age groups. Current treatments, including psychologica...
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A recent study reveals a troubling trend in how information about depression is presented to the public. Researchers found that major health organizations frequently provide misleading information, portraying depression as a disorder that causes symptoms rather than a descriptive label for those symptoms. This inaccuracy makes it harder for individuals to understand the real causes of their distress, potentially hindering effective treatment and emotional regulation. The findings, published in the journal Psychopathology, emphasize the need for clearer communication about mental health diagnos...
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An analysis of genetic data from the UK Biobank and the Psychiatric Genomics Consortium has indicated that individuals with higher estimated levels of omega-3 fatty acids in their bodies are less likely to suffer from major depressive disorder. The strongest association with lower depression risk was found for eicosapentaenoic acid, a long-chain omega-3 fatty acid. These findings were published in the journal Translational Psychiatry. Omega-3 fatty acids are a group of essential polyunsaturated fats crucial for maintaining overall health. The three main types are alpha-linolenic acid (ALA), wh...
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A recent study published in theInternational Journal of Geriatric Psychiatry reveals a significant link between depression and an increased risk of developing dementia. Conducted over 15 years, the study found that people with depression at the start of the study were 74% more likely to develop dementia than those without depression. Additionally, the onset of dementia occurred about two years earlier in individuals with depression. These findings underscore the importance of early detection and treatment of depression to potentially prevent future cognitive decline. The global population is a...
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A new study from Stanford Medicine introduces a groundbreaking method that combines brain imaging with machine learning to identify subtypes of depression, known as “biotypes,” and tailors treatments accordingly. Published inNature Medicine, the research categorizes depression into six distinct biotypes and identifies effective treatments for three of them. This innovative approach could lead to more personalized and effective treatment strategies for individuals suffering from depression and anxiety. Depression and anxiety disorders represent significant public health challenges worldwide. Tr...
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A recent study published in Behaviour Research and Therapy provides new insights into how young people manage their emotions and the potential impact on depression. The study found that nearly all adolescents use some maladaptive emotion regulation strategies, but this is not necessarily harmful if balanced with more adaptive strategies. Over time, the use of these maladaptive strategies generally decreases as adolescents grow older. However, an increase in the predominant use of maladaptive strategies is linked to heightened depression symptoms. Adolescence is a period marked by increased emo...
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A new study published in Developmental Cognitive Neuroscience sheds light on how early adversity affects brain development in children. Researchers found that greater adversity experienced during the perinatal period (around birth) is linked to smaller hippocampal volume in early childhood but also to faster growth in the right hippocampus throughout childhood. Interestingly, this accelerated growth was associated with an increased risk of depressive symptoms later in childhood. Previous research has indicated that children exposed to adversity often experience various developmental changes. H...
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